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NEUROMUSCULAR DISEASE MIMICKING MYASTHENIA GRAVIS IN A NIGERIAN FEMALE ADOLESCENT: COULD THIS BE NEMALINE ROD
O A Oyinlade1, I A Lagunju1, B E Adebayo1
1Department of Paediatrics, College of Medicine, University of Ibadan/University College Hospital, Ibadan.
Background:
Nemaline rod disease is a congenital myopathy, presentation of which may mimic myasthenia gravis.
Method:
We report a suspected case of nemaline rod disease in a female adolescent who presented with features similar to myasthenia gravis but failed to respond effectively to its conventional management. She had features of respiratory failure and cardiomyopathy.
Results:
Patient had a turbulent clinical course and finally succumbed to illness on the fifth day of admission.
Conclusion:
This report is meant to sensitize child neurologists and general paediatricians on the need to have a broad spectrum of considerations in the management of suspected myasthenia gravis, especially when response to anticholinesterase is poor.
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