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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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[Correlation between chronic constipation and colorectal neoplasms].

Baohua Liu1

  • 1Department of General Surgery, Center of Constipation Diagnosis and Treatment, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China. LBH57268@163.com.

Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery
|March 25, 2017
PubMed
Summary

Chronic constipation significantly increases colorectal polyp risk. While not a direct cause of colorectal cancer, it is a risk factor, necessitating careful laxative use and polyp monitoring.

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Area of Science:

  • Gastroenterology
  • Oncology
  • Epidemiology

Background:

  • Growing interest in the link between chronic constipation and colorectal neoplasms.
  • Numerous global epidemiological and clinical studies have investigated this association.

Purpose of the Study:

  • To analyze the correlation between constipation and colorectal neoplasms.
  • To examine the relationship from three perspectives: polyps, cancer, and melanosis coli (MC) with laxatives.

Main Methods:

  • Review and synthesis of existing domestic and international epidemiological and clinical research.
  • Analysis of data concerning constipation, colorectal polyps, colorectal cancer, MC, and laxative use.

Main Results:

  • Constipation significantly elevates the incidence of colorectal polyps.
  • Constipation is identified as a risk factor for colorectal cancer, though not a direct cause.
  • Melanosis coli (MC) and laxative use show a close correlation with the incidence of colorectal polyps.

Conclusions:

  • Colorectal polyps are recognized as precancerous lesions.
  • Patients with chronic constipation should limit the use of anthraquinone laxatives.
  • Periodic follow-up is recommended for individuals diagnosed with colorectal polyps.