Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Large benign virilizing adrenal adenoma.

R S Martin1, R F Grenfell, W H Cleland

  • 1Department of Surgery, University of Mississippi Medical Center.

Southern Medical Journal
|April 1, 1988
PubMed
Summary

A large adrenal tumor caused virilization and infertility in a young woman. Surgical removal of the benign tumor resolved virilization and led to pregnancy, highlighting an unusual presentation of adrenocortical tumors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A robust time-delay selection criterion applied to convergent cross mapping.

Chaos (Woodbury, N.Y.)·2024
Same author

Red blood cells in type 1 diabetes and multiple sclerosis and technologies to measure their emerging roles.

Journal of translational autoimmunity·2022
Same author

Assessments of fatigue and disease activity in patients with systemic lupus erythematosus enrolled in the Phase 2 clinical trial with blisibimod.

Lupus·2016
Same author

Characterization of the Etna volcanic emissions through an active biomonitoring technique (moss-bags): part 1--major and trace element composition.

Chemosphere·2014
Same author

A phase 2, randomised, placebo-controlled clinical trial of blisibimod, an inhibitor of B cell activating factor, in patients with moderate-to-severe systemic lupus erythematosus, the PEARL-SC study.

Annals of the rheumatic diseases·2014
Same author

Development of a full body CAD dataset for computational modeling: a multi-modality approach.

Annals of biomedical engineering·2011

Area of Science:

  • Endocrinology
  • Oncology
  • Reproductive Medicine

Background:

  • Adrenocortical tumors can present with diverse endocrine manifestations.
  • Virilization in women is often associated with androgen-secreting neoplasms.
  • Large adrenal masses raise concerns for malignancy.

Observation:

  • A young woman presented with infertility and signs of virilization.
  • Endocrine evaluation revealed a large left adrenal tumor with pure virilization and normal glucocorticoid function.
  • The tumor was surgically resected.

Findings:

  • Histopathology confirmed a benign adrenocortical tumor.
  • Post-operatively, the patient experienced regression of virilization.
  • The patient subsequently achieved pregnancy.

Related Experiment Videos

Implications:

  • Pure virilization can be an unusual presentation of benign adrenocortical tumors.
  • Surgical management of such tumors can restore endocrine function and fertility.
  • This case underscores the importance of thorough endocrine and oncologic evaluation for adrenal masses.