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Is the Future of Coronary Arterial Revascularization a Hybrid Approach?: The Canadian Experience Across Three Centers
Vincenzo Giambruno1, Ahmad Hafiz, Stephanie A Fox
1From the *Division of Cardiac Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada; †Division of Cardiac Surgery, University of Montreal, Montreal Heart Institute, Montreal, Quebec, Canada; ‡Division of Cardiac Surgery, University of British Columbia, St. Paul's Hospital, Vancouver, British Columbia, Canada; and §Division of Cardiology, Department of Medicine, ∥Department of Anesthesia and Perioperative Medicine, Western University, London Health Sciences Centre, London, Ontario, Canada.
Insights
Hybrid coronary revascularization combines surgical and percutaneous approaches, demonstrating excellent graft and stent patency. This safe strategy offers selected patients complete revascularization with minimal trauma and favorable long-term outcomes.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Minimally Invasive Procedures
Background:
- Hybrid coronary revascularization integrates surgical and percutaneous interventions to leverage their respective advantages.
- This approach aims to overcome the limitations inherent in isolated surgical or percutaneous coronary revascularization techniques.
Purpose of the Study:
- To evaluate graft and stent patency at 6 months post-procedure.
- To assess bleeding rates, intensive care unit (ICU) and hospital length of stay.
- To determine rates of reintervention and long-term clinical outcomes following hybrid coronary revascularization.
Main Methods:
- A total of 203 patients underwent robotic-assisted minimally invasive direct coronary artery bypass graft (MIDCAB) of the left internal thoracic artery (LITA) to the left anterior descending (LAD) artery and percutaneous coronary intervention (PCI) of a non-LAD vessel.
- Procedures were performed in a single or two stages across three centers between March 2004 and November 2015.
- Patients received 6-month angiographic follow-up and a mean clinical follow-up of 77.82 ± 41.4 months.
Main Results:
- Successful hybrid coronary revascularization was achieved in 196 out of 203 patients (96.6%).
- Mean ICU stay was 1 ± 1 days, mean hospital stay was 5 ± 2 days, and only 13.3% required blood transfusion.
- Six-month angiographic follow-up showed LITA anastomotic patency of 97.9% and stent patency of 92.6%. Long-term follow-up revealed 95.1% survival and 90.7% freedom from revascularization.
Conclusions:
- Hybrid coronary revascularization is a promising and safe strategy for selected patients.
- It provides functionally complete revascularization with reduced surgical trauma.
- The procedure is associated with favorable long-term clinical outcomes, including high survival and freedom from angina.
Objective:
Hybrid coronary revascularization offers and combines the advantages of both surgical and percutaneous revascularization and eliminates at the same time the disadvantages of both procedures. The objective of this study was to assess graft and stent patency at 6 months, rate of bleeding, intensive care unit and hospital stay, rate of reintervention, and long-term clinical follow-up.
Methods:
From March 2004 to November 2015, a total of 203 patients underwent robotic-assisted minimally invasive direct coronary artery bypass graft of the left internal thoracic artery to the left anterior descending artery and PCI of a non-left anterior descending vessel in a single or two stage, at three different centers. Patients underwent 6-month angiographic follow-up. The mean ± SD clinical follow-up was 77.82 ± 41.4 months.
Results:
Successful hybrid coronary revascularization occurred in 196 of the 203 patients. One hundred forty-six patients underwent simultaneous surgical and percutaneous intervention. Nineteen patients underwent PCI before surgery, and 38 patient underwent PCI after surgery. No in-hospital mortality occurred. The mean ± SD ICU stay was 1 ± 1 days and the mean ± SD hospital stay was 5 ± 2 days. Only 13.3% of the patients required a blood transfusion. Six-month angiographic follow-up has been performed in the 95 patients, and it demonstrated a left internal thoracic artery anastomotic patency of 97.9% and stent patency of 92.6%. A total of 77.8 ± 41.4-month clinical follow-up demonstrated 95.1% survival, 92.6% freedom from angina, and 90.7% freedom from any form of coronary revascularization.
Conclusions:
Hybrid coronary revascularization seems to be a promising and safe revascularization strategy. It provides selected patients with an alternative, functionally complete revascularization with minimal surgical trauma and good long-term clinical outcomes.
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