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Updated: Mar 5, 2026

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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Case Report: Immune-mediated Complete Response in a Patient With Recurrent Advanced Ewing Sarcoma (EWS) After Vigil

Maurizio Ghisoli1, McCarley Rutledge, Philip J Stephens

  • 1*Mary Crowley Cancer Research Centers †Texas Oncology, P.A. ‡Medical City Dallas Hospital ∥ProPath ¶Gradalis Inc. #Strike Bio, Dallas, TX §Foundation Medicine, Cambridge, MA.

Journal of Pediatric Hematology/Oncology
|March 25, 2017
PubMed
Summary

Ewing sarcoma is a rare cancer. A patient with recurrent metastatic Ewing sarcoma achieved a sustained complete response using Vigil (GMCSF/bi-shRNA furin DNA autologous tumor immunotherapy), suggesting its potential efficacy.

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