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Blood Pressure Control During Chronic Kidney Disease Progression
Seulbi Lee1, Hyung Jung Oh2,3, Eun-Kyung Lee1
1Department of Statistics, Ewha Womans University, Seoul, Korea.
American Journal of Hypertension
|March 25, 2017
Summary
Poor blood pressure control is common in chronic kidney disease (CKD) patients and worsens with CKD progression. Increased pulse pressure is a key factor linked to inadequate hypertension management in these individuals.
Area of Science:
- Nephrology
- Cardiology
- Public Health
Background:
- Hypertension is a leading cause of end-stage renal disease.
- Effective blood pressure (BP) management is critical for chronic kidney disease (CKD) patients.
- Inadequate BP control is prevalent among CKD patients.
Purpose of the Study:
- To determine the prevalence of inadequate BP control in CKD patients.
- To identify factors associated with poor BP control based on CKD stage.
Main Methods:
- Analysis of a large-scale health examination sample cohort database (2012-2013).
- Inclusion of 27,350 CKD patients (7.9% of 345,044 participants).
- Statistical analysis to identify factors associated with BP control.
Main Results:
- Poorly controlled hypertension increased significantly with CKD stage progression.
- Systolic BP rose with CKD stage; diastolic BP showed no significant difference.
- Factors associated with poor BP control included age, female sex, BMI, increased pulse pressure, CKD stage, fasting glucose, total cholesterol, hemoglobin, and proteinuria.
Conclusions:
- The prevalence of poorly controlled hypertension in CKD patients escalates with disease progression.
- Increased pulse pressure is a primary factor associated with inadequate BP control in hypertensive CKD patients.
- Further research is required to establish causal relationships between poor BP control and identified factors.
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