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Updated: Mar 5, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
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A case of severely calcified neoatherosclerosis after paclitaxel eluting stent implantation

Kei Yamamoto1, Kenichi Sakakura1, Yousuke Taniguchi1

  • 1Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.

Cardiovascular Revascularization Medicine : Including Molecular Interventions
|March 27, 2017
PubMed

Insights

This study details a case of calcified neoatherosclerosis in a paclitaxel-eluting stent (PES), a rare complication. Advanced imaging techniques like optical frequency domain imaging (OFDI) and intravascular ultrasound (IVUS) were crucial for diagnosis and treatment.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Biomedical Imaging

Background:

  • In-stent restenosis (ISR) is a significant complication after percutaneous coronary intervention (PCI).
  • Neoatherosclerosis, characterized by lipid-rich macrophages and calcification, is an underdiagnosed cause of ISR, particularly after drug-eluting stent (DES) implantation.
  • Distinguishing between different types of ISR is critical for effective treatment strategies.

Keywords:
In-stent restenosisNeoatherosclerosisPaclitaxel-eluting stentRotational atherectomy

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