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Capillary dysfunction is associated with symptom severity and neurodegeneration in Alzheimer's disease

Rune B Nielsen1, Lærke Egefjord2, Hugo Angleys1

  • 1Center of Functionally Integrative Neuroscience and MINDLab, Aarhus University, Aarhus, Denmark.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|March 28, 2017
PubMed
Abstract

Keywords:
Alzheimer's diseaseCapillary dysfunctionCapillary transit time heterogeneity (CTH)Cerebral blood flow (CBF)Cerebral blood volume (CBV)Cortical thinningHypoxiaMagnetic resonance imaging (MRI)Microvascular dysfunctionNeurodegenerationNeurovascular dysfunctionPerfusion imagingRelative transit time heterogeneity (RTH)Tissue oxygen tension (P(t)O(2))

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