Establishment of Over-The-Scope-Clips (OTSC®) in daily endoscopic routine

Area of Science:

• Gastroenterology
• Endoscopic Surgery
• Medical Devices

Background:

• The increasing complexity of interventional endoscopy necessitates advanced closure tools.
• Challenging indications require sophisticated endoscopic solutions for effective treatment.

Purpose of the Study:

• To evaluate the clinical utility and success rates of the Over-The-Scope-Clip (OTSC®).
• To assess OTSC® performance across diverse gastrointestinal indications in a real-world setting.

Main Methods:

• Retrospective analysis of 262 OTSC® placements in 233 endoscopic interventions.
• Follow-up focused on clinically lasting success for various indications.

Main Results:

• Immediate OTSC® success rate of 87.1% across all sessions.
• High immediate success for bleeding (84.8-100%), perforations (90.3-100%), and stent fixation (100%).
• 30-day success rates varied by indication, with anastomotic leakage (33.3%) and fistulae (29.8%) showing lower rates.

Conclusions:

• The OTSC® is clinically useful in daily endoscopic practice.
• Performance varies by indication, highlighting areas for further investigation and improvement.