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Will bevacizumab biosimilars impact the value of systemic therapy in gynecologic cancers?

Bradley J Monk1, Warner K Huh2, Julie Ann Rosenberg3

  • 1Arizona Oncology (US Oncology Network), University of Arizona College of Medicine, Creighton University School of Medicine at St. Joseph's Hospital, Phoenix, AZ USA.

Gynecologic Oncology Research and Practice
|March 28, 2017
PubMed
Abstract

Insights

Bevacizumab biosimilars are in development and may improve patient access to gynecologic cancer treatments. These biosimilars offer potential cost efficiencies for healthcare systems.

Area of Science:

  • Oncology
  • Pharmacology
  • Biotechnology

Background:

  • Bevacizumab is a key treatment for ovarian and cervical cancers.
  • Patient access to bevacizumab is currently limited.
  • Biosimilars offer similar efficacy and safety to reference biologics.

Purpose of the Study:

  • To review bevacizumab's role in gynecologic cancer treatment.
  • To explore the potential of bevacizumab biosimilars.
  • To discuss increased access to cancer therapies.

Main Methods:

  • Searched PubMed and ClinicalTrials.gov for relevant studies.
  • Reviewed regulatory and pharmaceutical company information.
  • Identified bevacizumab biosimilars in development.

Main Results:

  • Four bevacizumab biosimilar candidates are in clinical assessment.
  • Biosimilars have the potential to increase access to treatment.
  • These candidates may improve healthcare system efficiencies.

Conclusions:

  • Bevacizumab will remain crucial for gynecologic cancer treatment.
  • Bevacizumab biosimilars are under development.
  • Biosimilars may enhance patient access to gynecologic cancer therapies.
Keywords:
BevacizumabBiosimilarCervical cancerOvarian cancer

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