Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Fractionated heparins. The clinician's viewpoint].

A Larcan1

  • 1Service d'Urgence et de Réanimation, C.H.R. de Nancy.

Journal Des Maladies Vasculaires
|January 1, 1987
PubMed
Summary

Low molecular weight heparins require standardized dosing assessment for preventing thrombo-embolic disease. Current methods lack reliable biologic data for adjusting dosages effectively, impacting clinical use.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The School of War Surgery of the Faculty of Medicine of Nancy].

Histoire des sciences medicales·2001
Same author

[Eulogy for Jean-Charles Sournia (1917-2000)].

Bulletin de l'Academie nationale de medecine·2001
Same author

[A century of progress. From macrocirculation to microcirculation].

Journal des maladies vasculaires·2001
Same author

Evolution of lactate/pyruvate and arterial ketone body ratios in the early course of catecholamine-treated septic shock.

Critical care medicine·2000
Same author

Comparison of systemic and regional effects of dobutamine and dopexamine in norepinephrine-treated septic shock.

Intensive care medicine·1999
Same author

[Nephropathy caused by Amanita phalloides].

Presse medicale (Paris, France : 1983)·1999

Area of Science:

  • Pharmacology
  • Thrombosis Research
  • Clinical Medicine

Context:

  • Rapid advancement of low molecular weight heparins (LMWHs) necessitates clear clinical guidelines.
  • Existing prophylaxis protocols for thrombo-embolic disease require rigorous evaluation.
  • Comparison with established methods like Kakkar's is crucial for validating LMWH efficacy.

Purpose:

  • To assess the efficacy of low molecular weight heparins in preventing thrombo-embolic disease.
  • To compare LMWHs with existing standards in various surgical and medical contexts.
  • To determine optimal standardized dosing and treatment regimens for LMWHs.

Summary:

  • Standardized dosing of low molecular weight heparins presents challenges due to a lack of reliable biologic assays.
  • Current assays primarily measure heparin activity rather than clinical efficacy.
  • LMWHs may be useful in cases of relative contraindication for high molecular weight heparin.

Impact:

  • Improved clinical decision-making regarding LMWH use in thrombo-embolic prophylaxis.
  • Potential for development of more accurate and efficacy-based dosing strategies.
  • Enhanced patient safety through optimized heparin therapy in surgical and medical patients.

Related Experiment Videos