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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Rich Coordination Chemistry of π-Acceptor Dibenzoarsole Ligands
Arvind Kumar Gupta1, Sunisa Akkarasamiyo2, Andreas Orthaber1
1Molecular Inorganic Chemistry, Department of Chemistry, Ångström Laboratories, Uppsala University , Box 523, 751 20 Uppsala, Sweden.
Abstract:
A series of dibenzoarsole (also known as 9-arsafluorene) derivatives have been prepared, and their coordination chemistry has been investigated. The different ligand topology and the arsenic substituents govern the reactivity of the ligands. We report various crystal structures of palladium and platinum complexes derived from this family of ligands. The biphenyl backbone of the bridged bidentate ligands allows very flexible coordination. We have also studied the application of an allylic Pd complex in nucleophilic substitution reactions, revealing that the benzoarsole substituent is susceptible to metal insertion.
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