Peripheral and central fatigue after high intensity resistance circuit training
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Updated: Mar 5, 2026

Determining The Electromyographic Fatigue Threshold Following a Single Visit Exercise Test
Published on: July 27, 2015
Gonzalo Márquez1, Salvador Romero-Arenas1, Cristian Marín-Pagán2
1Department of Physical Education and Sport, Faculty of Sport Sciences, Catholic University of Murcia (UCAM), Murcia, Spain.
Introduction:
The aim of this study was to investigate the effects of high intensity resistance circuit (HIRC) and traditional strength training (TST) on neuromuscular fatigue and metabolic responses.
Methods:
Twelve trained young subjects performed HIRC and TST in a counterbalanced order with 1 week rest in-between. The amount of workload and the inter-set time for each local muscle group were matched (180 s), however, the time between successive exercises differed. The twitch interpolation technique was used to test neuromuscular function of the knee extensor muscles. Blood lactate concentration was used to evaluate metabolic responses.
Results:
Maximum voluntary contraction and resting potentiated twitch amplitude (Qtw ) were significantly reduced after HIRC, but there were not changes after TST, while reductions in voluntary activation were similar. Lactate concentration increased significantly more after HIRC.
Conclusions:
The higher lactate concentration after HIRC probably impaired excitation-contraction coupling, indicating larger peripheral fatigue than after TST. Muscle Nerve 56: 152-159, 2017.
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