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Related Concept Videos

Proteomics01:33

Proteomics

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A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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Updated: Mar 5, 2026

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
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Common bean proteomics: Present status and future strategies.

Sajad Majeed Zargar1, Reetika Mahajan2, Muslima Nazir1

  • 1Division of Biotechnology, SK University of Agricultural Sciences and Technology of Kashmir, Shalimar, Srinagar, Jammu & Kashmir 190025, India.

Journal of Proteomics
|March 29, 2017
PubMed
Summary

High-throughput omics approaches, particularly proteomics, are crucial for understanding common bean (Phaseolus vulgaris L.) genetics and improving its nutritional value. These methods help identify genes for stress tolerance and enhanced health benefits, ensuring food security.

Keywords:
Common beanGenomicsMarkersProteogenomicsProteomics

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Area of Science:

  • Plant Science
  • Genomics
  • Proteomics

Background:

  • Common bean (Phaseolus vulgaris L.) is a vital global food source, rich in protein, micronutrients, and health-promoting compounds.
  • Its productivity is significantly limited by biotic and abiotic stresses.
  • The recent common bean genome sequence provides a foundation for advanced genetic studies.

Purpose of the Study:

  • To highlight the necessity of proteomics in common bean research.
  • To explore the potential of proteomics in understanding stress responses and genetic regulation.
  • To discuss how proteogenomics can enhance nutritional improvement and identify key biological regulators.

Main Methods:

  • Review of high-throughput omics approaches, focusing on proteomics.
  • Analysis of proteomics' role in gene function determination and mining new genes.
  • Discussion of proteogenomics for nutritional enhancement and stress adaptation.

Main Results:

  • Proteomics offers a powerful tool to analyze gene functions and identify candidate genes for crop improvement under stress.
  • Proteogenomics can accelerate the discovery of molecular mechanisms underlying stress tolerance and nutritional quality.
  • Omics tools combined with breeding strategies are essential for sustainable legume production.

Conclusions:

  • Proteomics is indispensable for in-depth understanding of common bean biology, especially under stress conditions.
  • Future research should leverage proteomics and proteogenomics to mine genomic resources for enhanced crop traits.
  • Integrating omics with traditional breeding is key to improving common bean's contribution to global food security and human health.