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Perinatal and postnatal risk factors for disruptive mood dysregulation disorder at age 11: 2004 Pelotas Birth Cohort

Tiago N Munhoz1, Iná S Santos2, Aluísio J D Barros2

  • 1Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil; Faculty of Psychology, Federal University of Pelotas, Pelotas, Brazil.

Journal of Affective Disorders
|March 29, 2017
PubMed

Insights

Maternal mental health during pregnancy and after childbirth, along with lower maternal education, are key risk factors for disruptive mood dysregulation disorder (DMDD) in children by age 11. Early intervention in maternal well-being may prevent future psychiatric disorders.

Area of Science:

  • Child and Adolescent Psychiatry
  • Developmental Psychology
  • Perinatal Mental Health

Background:

  • Disruptive Mood Dysregulation Disorder (DMDD) is a condition with limited research on early life risk factors.
  • Understanding perinatal and postnatal influences is crucial for identifying children at risk for DMDD.

Purpose of the Study:

  • To investigate perinatal and postnatal risk factors associated with the development of DMDD by 11 years of age.
  • To identify modifiable maternal characteristics linked to DMDD onset.

Main Methods:

  • A prospective longitudinal study involving 3563 subjects assessed at 11 years of age.
  • Mothers completed questionnaires post-childbirth; DMDD was identified using the Development and Well-Being Assessment.
  • Logistic regression analyses were performed to identify risk factors.

Main Results:

  • The prevalence of DMDD by age 11 was 2.5%.
  • Significant early risk factors included maternal mood symptoms during pregnancy, maternal depression post-childbirth, and lower maternal education levels.
  • These findings were adjusted for potential confounders.

Conclusions:

  • Early risk factors for DMDD are primarily linked to modifiable maternal characteristics.
  • DMDD is a predictor of subsequent psychiatric disorders like depression and anxiety.
  • Targeted prenatal and postnatal mental healthcare could be preventative for offspring mental health issues.
Abstract

Keywords:
Adolescent psychiatryEpidemiologyMental disordersMental disorders diagnosed in childhoodMood disordersNeurodevelopmental disorders

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