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Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization

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Letter re: A genome-wide association study in multiple system atrophy

Shoji Tsuji1, Jun Mitsui1

  • 1Tokyo.

Neurology
|March 29, 2017
PubMed
Summary

No abstract available in PubMed .

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Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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