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[Parvoviruses as pathogenic agents in man].

J D Tratschin1, G Siegl

  • 1Institut für Hygiene und medizinische Mikrobiologie der Universität Bern.

Schweizerische Medizinische Wochenschrift
|March 12, 1988
PubMed
Summary

Human parvovirus infections, including parvovirus B19 causing fifth disease, are increasingly reported. This review covers human parvoviruses, their associated diseases, and diagnostic limitations.

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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Context:

  • Since 1981, there has been a notable rise in reported human parvovirus infections.
  • Parvovirus B19 is definitively linked to erythema infectiosum (fifth disease).
  • Other human parvoviruses are implicated in enteritis and rheumatoid arthritis.

Purpose:

  • To review current knowledge on the biological characteristics of human parvoviruses.
  • To summarize the pathogenic relevance of human parvoviruses.
  • To discuss the diagnostic capabilities and constraints for parvovirus infections.

Summary:

  • Parvovirus B19 is associated with aplastic crisis in hemolytic anemia patients, arthropathies in adult women, and adverse pregnancy outcomes like hydrops foetalis.
  • The review consolidates information on parvovirus B19 and other emerging human parvoviruses.
  • It examines the clinical manifestations and epidemiological trends of these viral infections.

Impact:

  • Provides a comprehensive overview for clinicians and researchers on human parvovirus pathogens.
  • Highlights the significance of parvoviruses in various clinical settings, from childhood exanthems to pregnancy complications.
  • Informs diagnostic strategies and underscores the need for continued research into these viruses.

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