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Updated: Mar 5, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Malignant Hepatic Epithelioid Hemangioendothelioma with Villaret Syndrome
Hanchanale Pavan1, Joy Varghese1, Kavya Harika1
1Institute of Liver Disease & Transplantation, Department of Pathology, Global Health City, Chennai, India.
Abstract:
Malignant hepatic epithelioid hemangioendothelioma is a rare, vascular tumor of the liver with peak incidence in the middle age with a female preponderance and of unknown etiology. Majority of the tumors are asymptomatic. The gold standard for diagnosis of the tumor is liver histology showing presence of epithelioid tumor cells on a background of a hyaline stroma. Immunohistochemical positivity for CD31, CD34, Factor VIII, and Podoplanin (D2-40) is confirmatory. The treatment of choice is liver transplantation.
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