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Tuberculosis in a case of hyper immunoglobulin E syndrome
1Department of Pediatrics, Pediatric TB Clinic, B. J. Wadia Hospital for Children, Mumbai, Maharashtra, India.
Journal of Family Medicine and Primary Care
|March 29, 2017
Summary
Hyper immunoglobulin E syndrome (HIES) is a rare immunodeficiency. This report details a rare case of abdominal tuberculosis (TB) in a 15-year-old boy with HIES, highlighting uncommon mycobacterial infections.
Area of Science:
- Immunology
- Infectious Diseases
- Genetics
Background:
- Hyper immunoglobulin E syndrome (HIES) is a primary immunodeficiency characterized by high IgE levels, eczema, and recurrent infections.
- Staphylococcus aureus is the most common pathogen in HIES patients.
- Mycobacterial infections, including tuberculosis (TB), are rare in HIES.
Observation:
- A 15-year-old boy with diagnosed HIES developed abdominal tuberculosis.
- This case represents an uncommon presentation of mycobacterial infection in a patient with HIES.
Findings:
- The case highlights the potential for unusual infections in HIES patients.
- Tuberculosis can occur in individuals with Hyper immunoglobulin E syndrome, albeit infrequently.
Implications:
- This case broadens the understanding of potential infections in HIES.
- Clinicians should consider TB in HIES patients presenting with relevant symptoms.
- Further research into the susceptibility of HIES patients to mycobacterial infections is warranted.
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