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Updated: Mar 5, 2026

Arabidopsis thaliana Polar Glycerolipid Profiling by Thin Layer Chromatography TLC Coupled with Gas-Liquid Chromatography GLC
Published on: March 18, 2011
Regulation of thermoTRPs by lipids
Sara L Morales-Lázaro1, Luis Lemus1, Tamara Rosenbaum1
1Department of Cognitive Neuroscience, Instituto de Fisiología Celular, Circuito exterior s/n, Universidad Nacional Autónoma de México , Coyoacan, México City, Mexico.
Abstract:
The family of Transient Receptor Potential (TRP) ion channels is constituted by 7 subfamilies among which are those that respond to temperature, the thermoTRPs. These channels are versatile molecules of a polymodal nature that have been shown to be modulated in various fashions by molecules of a lipidic nature. Some of these molecules interact directly with the channels on specific regions of their structures and some of these promote changes in membrane fluidity or modify their gating properties in response to their agonists. Here, we have discussed how some of these lipids regulate the activity of thermoTRPs and included some of the available evidence for the molecular mechanisms underlying their effects on these channels.
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