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Molecular Imprinting Applications in Forensic Science.

Erkut Yılmaz1, Bora Garipcan2, Hirak K Patra3

  • 1Department of Biotechnology and Molecular Biology, Aksaray University, 68100 Aksaray, Turkey. yilmazerkut@yandex.com.

Sensors (Basel, Switzerland)
|March 29, 2017
PubMed
Summary

Molecular imprinting polymers (MIPs) offer selective recognition, stability, and ease of production for forensic science applications. This review highlights their current uses and future potential in analyzing illicit drugs, toxins, and more.

Keywords:
analytical methodsforensic sciencemolecular imprintingpre-concentrationtoxicology

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Area of Science:

  • Forensic Chemistry
  • Materials Science
  • Analytical Chemistry

Background:

  • Molecular imprinting-based materials are gaining attention for their selective recognition, stability, and ease of production.
  • These materials have diverse applications in food, environmental monitoring, and medicine, including sample pretreatment, sensing, and separation.
  • Their versatility and recognition capabilities make them suitable for demanding forensic science applications.

Purpose of the Study:

  • To review recent molecular imprinting applications in forensic science over the last two decades.
  • To consider both direct forensic applications and studies with potential forensic value.
  • To summarize current uses and project future potential of MIPs in forensic science.

Main Methods:

  • Literature review of over 100 articles focusing on molecular imprinting in forensic science.
  • Classification of literature based on targets, material shapes, production strategies, detection methods, and instrumentation.
  • Inclusion of studies on illicit drugs, banned sport drugs, toxins, and chemical warfare agents.

Main Results:

  • Molecularly imprinted polymers (MIPs) demonstrate significant potential in forensic science due to their unique properties.
  • Applications span the analysis of various substances relevant to forensic investigations.
  • The review categorizes MIPs based on key parameters like target analytes and detection methodologies.

Conclusions:

  • MIPs are promising alternatives to conventional methods in forensic science.
  • Continued research and development could expand their role in forensic analysis.
  • Their selectivity and stability offer advantages for identifying critical substances.