Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pneumothorax-I01:26

Pneumothorax-I

1.8K
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
1.8K
Pneumothorax-II01:27

Pneumothorax-II

1.2K
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
1.2K
Development of the Lymphatic System01:15

Development of the Lymphatic System

2.4K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
2.4K
Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

24.0K
Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...
24.0K
Trachea01:22

Trachea

5.6K
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
5.6K
Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

960
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
960

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of patent ductus arteriosus - Evidence to practice.

Seminars in fetal & neonatal medicine·2024
Same author

Ethical and Legal Perspectives on the Treatment of Hypoxic Ischemic Encephalopathy in the Newborn.

Clinics in perinatology·2024
Same author

Risk of death at home or on hospital readmission after discharge with pediatric tracheostomy.

Journal of perinatology : official journal of the California Perinatal Association·2023
Same author

Previous missed visits and independent risk of loss to follow-up in the high-risk neonatal follow-up clinic.

Early human development·2023
Same author

Back Transfer of Infants with Tracheostomies: A Regional Center Experience.

Journal of pediatric intensive care·2023
Same author

Pulmonary hypertension in the newborn - Towards precision medicine.

Seminars in fetal & neonatal medicine·2022
Same journal

Strategies for prevention of intraventricular hemorrhage in the neonatal intensive care unit.

Seminars in fetal & neonatal medicine·2026
Same journal

Introduction.

Seminars in fetal & neonatal medicine·2026
Same journal

Introduction.

Seminars in fetal & neonatal medicine·2026
Same journal

Should inhaled nitric oxide be used for respiratory failure in preterm infants?

Seminars in fetal & neonatal medicine·2026
Same journal

Inhaled nitric oxide in premature infants for respiratory failure: Discussion and consensus.

Seminars in fetal & neonatal medicine·2026
Same journal

Critical thinking in red blood cell transfusion decisions: Donor, product, recipient, and outcomes.

Seminars in fetal & neonatal medicine·2026
See all related articles

Related Experiment Video

Updated: Mar 5, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

15.0K

Congenital chylothorax.

Mohammad A Attar1, Steven M Donn1

  • 1Department of Pediatrics and Communicable Diseases, Division of Neonatal-Perinatal Medicine, C.S. Mott Children's Hospital, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.

Seminars in Fetal & Neonatal Medicine
|March 30, 2017
PubMed
Summary
This summary is machine-generated.

Congenital chylothorax (CC) is a rare condition often linked to lymphatic abnormalities. While many cases resolve spontaneously, evidence-based treatments are needed to improve outcomes for severe fetal and neonatal cases.

Keywords:
Hydrops fetalisHydrothoraxLymphoscintigraphyNeonatalPulmonary

More Related Videos

Transuterine Fetal Tracheal Occlusion Model in Mice
06:31

Transuterine Fetal Tracheal Occlusion Model in Mice

Published on: February 5, 2021

3.6K
Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
04:14

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Published on: February 28, 2025

947

Related Experiment Videos

Last Updated: Mar 5, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

15.0K
Transuterine Fetal Tracheal Occlusion Model in Mice
06:31

Transuterine Fetal Tracheal Occlusion Model in Mice

Published on: February 5, 2021

3.6K
Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
04:14

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Published on: February 28, 2025

947

Area of Science:

  • Pediatrics
  • Neonatology
  • Cardiovascular Research

Background:

  • Congenital chylothorax (CC) arises from lymphatic vessel anomalies or thoracic defects, potentially causing fetal demise.
  • Pleural fluid accumulation in CC impairs lung development and cardiovascular function, with additional risks from lymphatic content loss.
  • Prenatal interventions may enhance survival in severe fetal chylothorax cases.

Purpose of the Study:

  • To review current understanding and treatment strategies for congenital chylothorax.
  • To highlight the need for evidence-based guidelines in managing CC.
  • To identify data gaps regarding the efficacy and safety of CC interventions.

Main Methods:

  • Review of existing literature on congenital chylothorax.
  • Analysis of current diagnostic and therapeutic approaches.
  • Identification of areas requiring further research in CC management.

Main Results:

  • Congenital chylothorax is associated with significant risks to fetal and neonatal health.
  • Current neonatal management is primarily supportive, involving thoracostomy drainage and conservative measures to reduce chyle flow.
  • Limited data exists on the efficacy and safety of specific interventions for CC.

Conclusions:

  • Most congenital chylothorax cases resolve spontaneously over time.
  • There is a critical need for robust, evidence-based treatment guidelines for CC.
  • Further research is essential to establish optimal diagnostic and therapeutic strategies for congenital chylothorax.