Related Experiment Video
Updated: Mar 5, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Brain edema with clasmatodendrosis complicating ataxia telangiectasia
Konomi Shimoda1, Masakazu Mimaki1, Shuhei Fujino1
1Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Japan.
Abstract:
Ataxia-telangiectasia is a chronic progressive disorder affecting the nervous and immune systems, caused by a genetic defect in the ATM protein. Clasmatodendrosis, a distinct form of astroglial death, has rarely been reported in ataxia-telangiectasia. Neuropathology of our patient disclosed diffuse edema of the cerebral and cerebellar white matter with prominent clasmatodendrosis, implicating ATM in the regulation of astroglial cell death.
More Related Videos
08:41Author Spotlight: Deciphering the Role of ATM in Ataxia-Telangiectasia and the Associated Cerebellar Degeneration
Published on: December 27, 2024
10:50Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo
Published on: March 26, 2019