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Arterial hypertension and aortic valve stenosis: Shedding light on a common "liaison"
Charalampos I Liakos1, Charalampos A Grassos2, Dimitrios P Papadopoulos3
1ESH Centre of Excellence for Hypertension, 1st Cardiology Department, "Hippokration" Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Insights
Arterial hypertension and aortic valve stenosis often coexist, particularly in older adults. This review examines their complex interaction, guiding physicians on diagnosis and treatment for better patient outcomes.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Arterial hypertension and aortic valve stenosis are prevalent, frequently co-occurring conditions, especially in the elderly.
- Hypertension significantly impacts cardiac hemodynamics, influencing the presentation of coexisting valvular heart disease like aortic stenosis.
- Current European and American guidelines offer limited discussion on the interplay between hypertension and valvular heart disease management.
Purpose of the Study:
- To review existing evidence on the interaction between hypertension and aortic valve stenosis.
- To aid physicians in understanding the pathophysiology of this combined condition.
- To guide the selection of optimal diagnostic and therapeutic strategies for managing these high-risk patients.
Main Methods:
- Systematic review of available scientific literature.
- Analysis of studies focusing on the interplay between arterial hypertension and aortic valve stenosis.
- Evaluation of diagnostic and therapeutic approaches in current guidelines.
Main Results:
- Hypertension substantially affects hemodynamic load in patients with aortic stenosis.
- The combined presence of these conditions requires careful consideration for effective management.
- Evidence suggests a need for integrated approaches in guidelines for managing concomitant hypertension and aortic valve stenosis.
Conclusions:
- Understanding the pathophysiology of combined hypertension and aortic valve stenosis is crucial for clinical practice.
- Physicians need clear strategies for diagnosis and treatment, balancing risks and benefits.
- Further research and guideline integration are necessary for optimal patient care and outcomes.
Abstract:
Arterial hypertension and aortic valve stenosis are common disorders and frequently present as concomitant diseases, especially in elderly patients. The impact of hypertension on heart haemodynamics is substantial, thus affecting the clinical presentation of any coexisting valvulopathy, especially of aortic stenosis. However, the interaction between these 2 entities is not thoroughly discussed in the European or/and American guidelines on the management of hypertension or/and valvular heart disease. The present review summarizes all available evidence on the potential interplay between hypertension and aortic valve stenosis, aiming to help physicians understand the pathophysiology and select the best diagnostic and therapeutic strategies (medical or/and interventional) for better management of these high-risk patients, taking into account the impact on outcome as well as the risk-benefit-ratio.
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