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Profile of glomerular diseases associated with hepatitis B and C: A single-center experience from India

Nishad Raveendran1, Pankaj Beniwal1, Amith Vijay Leon D'Souza1

  • 1Department of Nephrology, SMS Medical College, Jaipur, Rajasthan, India.

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|March 30, 2017
PubMed

Insights

Hepatitis B and C infections can cause kidney damage, leading to various glomerular diseases. This study found membranous nephropathy common in Hepatitis B patients and membranoproliferative glomerulonephritis in Hepatitis C patients.

Area of Science:

  • Nephrology
  • Hepatology
  • Immunology

Background:

  • Hepatitis B and C infections are linked to kidney disease.
  • Various glomerular diseases can arise from these viral infections.

Purpose of the Study:

  • To investigate the prevalence and types of glomerular diseases in patients with Hepatitis B and C.
  • To identify the most common glomerulonephritis in each viral infection group.

Main Methods:

  • Retrospective analysis of kidney biopsy data.
  • Inclusion of 534 patients undergoing kidney biopsy.
  • Categorization of glomerular diseases based on viral hepatitis status.

Main Results:

  • Hepatitis B was associated with glomerular disease in 2.9% of patients (16 cases).
  • Hepatitis C was associated with glomerular disease in 2.05% of patients (11 cases).
  • Membranous nephropathy was the most frequent glomerular disease in Hepatitis B patients.
  • Membranoproliferative glomerulonephritis was the most frequent glomerular disease in Hepatitis C patients.

Conclusions:

  • Hepatitis B and C infections are significant causes of glomerular diseases.
  • Specific patterns of glomerulonephritis are associated with Hepatitis B and C.
  • Kidney biopsy is crucial for diagnosing viral hepatitis-associated nephropathies.

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