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Antifreeze poisoning: A case report
Xiaofei Wu1, Guoyu Lu1, Benquan Qi1
1Department of Emergency Internal Medicine, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, P.R. China.
This case study highlights antifreeze poisoning in a 35-year-old male, emphasizing early recognition of symptoms like nausea and agitation. Prompt hemodialysis and comprehensive treatment led to significant recovery and improved renal function.
Area of Science:
- Toxicology
- Nephrology
- Emergency Medicine
Background:
- Antifreeze poisoning is a serious medical emergency.
- Early identification of clinical manifestations is crucial for timely intervention.
Purpose of the Study:
- To summarize the clinical manifestations and treatments of antifreeze poisoning.
- To enhance the recognition and management of antifreeze poisoning cases.
Main Methods:
- Case report analysis of a 35-year-old male with antifreeze poisoning.
- Review of clinical manifestations, laboratory findings, and treatment protocols.
- Comparison with existing literature on antifreeze poisoning.
Main Results:
- The patient presented with nausea, agitation, severe metabolic acidosis, renal dysfunction, and hyperkalemia.
- Hemodialysis resulted in initial improvement; subsequent treatment included mannitol, furosemide, Xuebijing, and reduced glutathione.
- Renal function, initially deteriorating, improved with comprehensive medical management.
Conclusions:
- Antifreeze poisoning requires prompt clinical recognition and active management, including hemodialysis.
- A multi-faceted treatment approach is effective in managing severe antifreeze poisoning and its complications.
- Early and accurate diagnosis significantly improves patient outcomes in antifreeze poisoning cases.
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