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Antifreeze poisoning: A case report.

Xiaofei Wu1, Guoyu Lu1, Benquan Qi1

  • 1Department of Emergency Internal Medicine, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, P.R. China.

Experimental and Therapeutic Medicine
|March 30, 2017
PubMed
Summary

This case study highlights antifreeze poisoning in a 35-year-old male, emphasizing early recognition of symptoms like nausea and agitation. Prompt hemodialysis and comprehensive treatment led to significant recovery and improved renal function.

Keywords:
antifreeze poisoningcase reporthemodialysis

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Area of Science:

  • Toxicology
  • Nephrology
  • Emergency Medicine

Background:

  • Antifreeze poisoning is a serious medical emergency.
  • Early identification of clinical manifestations is crucial for timely intervention.

Purpose of the Study:

  • To summarize the clinical manifestations and treatments of antifreeze poisoning.
  • To enhance the recognition and management of antifreeze poisoning cases.

Main Methods:

  • Case report analysis of a 35-year-old male with antifreeze poisoning.
  • Review of clinical manifestations, laboratory findings, and treatment protocols.
  • Comparison with existing literature on antifreeze poisoning.

Main Results:

  • The patient presented with nausea, agitation, severe metabolic acidosis, renal dysfunction, and hyperkalemia.
  • Hemodialysis resulted in initial improvement; subsequent treatment included mannitol, furosemide, Xuebijing, and reduced glutathione.
  • Renal function, initially deteriorating, improved with comprehensive medical management.

Conclusions:

  • Antifreeze poisoning requires prompt clinical recognition and active management, including hemodialysis.
  • A multi-faceted treatment approach is effective in managing severe antifreeze poisoning and its complications.
  • Early and accurate diagnosis significantly improves patient outcomes in antifreeze poisoning cases.