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Updated: Mar 5, 2026

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
Published on: January 25, 2019
Quality Assured Characterization of Stem Cells for Safety in Banking for Clinical Application
Kevin W Bruce1, John D M Campbell2, Paul De Sousa3,4
1Censo Biotechnologies Ltd and Roslin Cell Sciences Ltd, Wallace Building, Roslin BioCentre, Midlothian, EH25 9PP, UK. Kevin.Bruce@roslincs.com.
Abstract:
The promise of human pluripotent stem cells to serve as a scalable and renewable starting material for "off the shelf" therapeutic cell products to repair or replace cells and tissues damaged by disease or injury is unparalleled. Whether originating from embryos or the genetic manipulation of adult tissue-derived cells, this prospective impact dictates a comprehensive yet practicable standard of quality assured characterization, blending existing and bespoke standards and considerations. Here, we provide a guide to qualifying the suitability of this resource for human clinical application.
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