Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mechanisms for post-inflammatory hyperpigmentation and hypopigmentation.

J J Nordlund1, Z A Abdel-Malek

  • 1Department of Dermatology, University of Cincinnati College of Medicine, Ohio 45267.

Progress in Clinical and Biological Research
|January 1, 1988
PubMed
Summary

Inflammation triggers skin pigment changes, causing hyperpigmentation and hypopigmentation. Further research is needed to identify the specific biochemical pathways and mediators involved in these post-inflammatory skin conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Journey through the spectacular landscape of melanocortin 1 receptor.

Pigment cell & melanoma research·2024
Same author

Vitiligo: current medical and scientific understanding.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia·2011
Same author

What are melanocytes really doing all day long...?

Experimental dermatology·2009
Same author

Confusions about colour: a classification of discolorations of the skin.

The British journal of dermatology·2006
Same author

The safety of hydroquinone.

Journal of the European Academy of Dermatology and Venereology : JEADV·2006
Same author

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?

British journal of cancer·2006

Area of Science:

  • Dermatology
  • Cell Biology
  • Biochemistry

Background:

  • Post-inflammatory hyperpigmentation and hypopigmentation are common sequelae of skin inflammation.
  • The precise molecular mechanisms underlying these pigmentary changes are not fully elucidated.

Purpose of the Study:

  • To highlight the likely involvement of numerous unidentified inflammatory mediators and biochemical pathways in post-inflammatory pigmentary alterations.
  • To stimulate further research into the complex interplay of factors affecting epidermal and melanocyte function.

Main Methods:

  • This report is a conceptual review, synthesizing existing knowledge and proposing future research directions.
  • It does not present new experimental data but rather theoretical frameworks.

Related Experiment Videos

Main Results:

  • The study identifies a significant gap in understanding the specific mediators and pathways responsible for post-inflammatory pigment changes.
  • It emphasizes the need for targeted investigations to unravel these complex biological processes.

Conclusions:

  • Numerous unidentified inflammatory mediators and biochemical pathways are implicated in post-inflammatory hyperpigmentation and hypopigmentation.
  • Future research is crucial to elucidate these mechanisms, thereby improving the understanding of epidermal function and the role of melanocytes.