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Intra-articular hyaluronic acid is superior to steroids in knee osteoarthritis: A comparative, randomized study
Raju Vaishya1, Ramsagar Pandit1, Amit Kumar Agarwal1
1Department of Orthopaedics and Joint Replacement Surgery, Indraprastha Apollo Hospitals, New Delhi 110076, India.
Background:
To compare the short and mid-term results of intraarticular triamcinolone hexacetonide and hyaluronic acid (HA) in knee osteoarthritis.
Methods:
A prospective randomized study including 40 patients in steroid and 42 patients in HA group. The outcome was evaluated with Knee Society Score (KSS) and Visual Analog Scale (VAS).
Result:
On KSS function and VAS score, there was no difference till four weeks. On KSS pain there was no difference till 12 weeks (P > 0.05) after that score of steroid group deteriorated rapidly. At six months HA was significantly better than a steroid.
Conclusion:
The HA seems to be better for pain relief and functionality in the short and mid-term periods.