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Yeast/herpes simplex virus thymidine kinase gene fusions yield fusion proteins with thymidine kinase activity
1Department of Biology, York University, Downsview, Ontario, Canada.
Current Genetics
|January 1, 1985
Abstract:
Expression in Saccharomyces cerevisiae of the Herpes Simplex Virus type-1 (HSV-1) thymidine kinase gene was accomplished by the construction of a gene fusion between the TK and a yeast gene. The fusion of yeast DNA sequences (which include a promoter and DNA that codes for the amino terminus end of the yeast gene product) with the TK gene resulted in a protein fusion with thymidine kinase activity.