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Osteophyte induced lung fibrosis prevalence and osteophyte qualities predicting disease
Mary Salvatore1, Claudia I Henschke1, Rowena Yip1
1Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Objective:
To determine the prevalence of osteophyte induced lung fibrosis (OIF) and its relationship to osteophyte size, location, and surrounding fat.
Methods:
94 CT scans of the chest were reviewed, size of the largest osteophyte and the presence of fibrosis were recorded.
Results:
Presence of fibrosis was higher among patient with large (>10 mm) osteophytes compared to those with small (1-10mm) osteophytes. Age and presence of periosteophyte fat were significantly associated with presence of fibrosis.
Conclusions:
As the size of an osteophyte increases, there is a greater likelihood of lung fibrosis. Subpleural fat protects the lung from OIF.