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Technical Applications of Microelectrode Array and Patch Clamp Recordings on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
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Recent developments in the science of proarrhythmic cardiac safety of new drugs

J Rick Turner1, Dilip R Karnad2, Christopher H Cabell3

  • 1Cardiac Safety Services, QuintilesIMS, 4820 Emperor Blvd, Durham, NC 27703, USA.

European Heart Journal. Cardiovascular Pharmacotherapy
|April 1, 2017
PubMed

Keywords:
Brugada syndromeExposure-response modellingHuman induced pluripotent stem-cell derived cardiomyocytesIn silico modellingShort QT syndromeT-wave morphologyThorough QT/QTc studyTorsades de PointesTpe

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