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[Gardner-Diamond syndrome in a young man: A case report and literature review]
P Henneton1, M Frank2, E Litvinova3
1Centre de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France; Médecine interne et médecine vasculaire, hôpital Saint-Éloi, CHRU de Montpellier, 34295 Montpellier cedex 5, France.
Introduction:
Gardner-Diamond syndrome is a rare condition secondary to a sensitization to self-erythrocytes. It is predominantly seen in women and presents as a painful ecchymotic disorder. An underlying psychiatric disease or a triggering psychological stress is of important diagnostic value.
Case Report:
We report a 24-year-old patient who presented with intermittent spontaneous painful ecchymosis since 5 years. Complementary investigations failed to identify an organic disorder. Gardner-Diamond syndrome was retained because of the clinical presentation, the negativity of diagnostic work-up and the identification of a psychological trauma. Patient management (pain, psychological support) is difficult, justifying a multidisciplinary approach.
Conclusion:
Gardner-Diamond syndrome is a rare and unrecognized disorder, which should be discussed in the presence of ecchymotic or purpuric lesions that do not have a diagnostic orientation. Early recognition of this disorder enables initiation of an appropriate management, but also limits unnecessary additional explorations.