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Lipids Can Make Them Stick Together
1Laboratory for the Structure and Function of Biological Membranes, Center for Structural Biology and Bioinformatics, Université Libre de Bruxelles, CP 206/02, Bd du Triomphe, 1050 Brussels, Belgium.
Trends in Biochemical Sciences
|April 2, 2017
Abstract:
To be active, membrane proteins often need to assemble into multimers either transiently or permanently. Using high-end mass spectrometry (MS), Robinson and colleagues show that the formation of transient multimers may require lipids at the interface while stable oligomers appear not to require such help.