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Related Experiment Videos

Viscoelastic Testing in Trauma.

Mathijs R Wirtz1,2, Holger M Baumann3, J Henriëtte Klinkspoor4

  • 1Trauma Unit, Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.

Seminars in Thrombosis and Hemostasis
|April 2, 2017
PubMed
Summary

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Traumatic-induced coagulopathy (TIC) requires accurate diagnostics for effective therapy. Viscoelastic hemostatic assays (VHA) show promise in diagnosing TIC, guiding treatment, and predicting patient outcomes.

Area of Science:

  • Trauma and Emergency Medicine
  • Hematology
  • Clinical Diagnostics

Background:

  • Traumatic-induced coagulopathy (TIC) is a critical complication following severe trauma.
  • Early and precise diagnosis of TIC is essential for timely and effective therapeutic interventions.
  • Standard laboratory tests may not fully capture the dynamic nature of coagulopathy in trauma patients.

Purpose of the Study:

  • To review the current evidence on the application of viscoelastic hemostatic assays (VHA) in the diagnosis and management of TIC.
  • To evaluate the role of VHA in monitoring treatment efficacy for bleeding trauma patients.
  • To assess the prognostic value of VHA in predicting outcomes for patients with TIC.

Main Methods:

  • This narrative review synthesized existing literature on the use of VHA in trauma-induced coagulopathy.

Related Experiment Videos

  • Searches included studies on VHA for diagnosis, treatment guidance, and outcome prediction in trauma.
  • The review also considered identified limitations and pitfalls associated with VHA use.

    • Main Results:

    • VHA are increasingly recognized for their ability to provide rapid, comprehensive hemostatic information.
    • Evidence supports the use of VHA for diagnosing TIC and guiding the administration of blood products.
    • VHA can effectively monitor treatment response and may have prognostic implications in trauma patients.

    Conclusions:

    • Viscoelastic hemostatic assays offer valuable insights into the diagnosis, management, and prognosis of traumatic-induced coagulopathy.
    • Further research is warranted to optimize VHA protocols and fully integrate them into trauma care algorithms.
    • Understanding the limitations of VHA is crucial for accurate interpretation and clinical decision-making.