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Fast assembling of neuron fragments in serial 3D sections
Hanbo Chen1,2, Daniel Maxim Iascone3, Nuno Maçarico da Costa1
1Allen Institute for Brain Science, Seattle, WA, USA.
Brain Informatics
|April 3, 2017
Abstract:
Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons.