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Stent technology in ischemic stroke.

Nam K Yoon¹, Al-Wala Awad¹, M Yashar S Kalani¹

¹Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah.

Neurosurgical Focus

|April 4, 2017

Summary

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Stenting offers a safe endovascular treatment for stroke caused by cerebral atherosclerosis when medical options fail. This review covers stent technology, studies, and future innovations for treating blocked arteries.

Area of Science:

Neurology
Vascular Surgery
Biomedical Engineering

Background:

Cerebral atherosclerosis is a leading cause of stroke globally.
Refractory cases may necessitate revascularization procedures.
Endovascular treatment is a preferred, safe alternative to open surgery.

Purpose of the Study:

To provide an overview of stent technology for ischemic stroke treatment.
To discuss major studies on stenting for cerebrovascular atherosclerosis.
To explore current and future developments in stent technology.

Main Methods:

Review of major clinical studies on stent application in stroke.
Analysis of commonly used stent characteristics and limitations.
Discussion of emerging stent technologies and research directions.

Keywords:

BMS = bare-metal stent BVS = bioresorbable vascular scaffold CAS = carotid artery stenting CAVATAS = Carotid and Vertebral Artery Transluminal Angioplasty Study CCA = common carotid artery CE = Confirmité Européene CEA = carotid endarterectomy DEB = drug-eluting balloon DES = drug-eluting stent ISR = in-stent restenosis PED = Pipeline Embolization Device SAMMPRIS = Stenting and Aggressive Medical Therapy for Preventing Recurrent Stroke in Intracranial Stenosis TZD = thiazolidinedione VAS = vertebral artery stenosis WASID = Warfarin–Aspirin Symptomatic Intracranial Disease atherosclerotic disease carotid endarterectomy ischemic stroke stent

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Main Results:

Endovascular stenting is a viable option for specific atherosclerotic cerebrovascular diseases.
Various stent types have distinct technical profiles and limitations.
Ongoing research focuses on improving stent efficacy and safety.

Conclusions:

Stent technology is crucial in managing complex atherosclerotic cerebrovascular disease.
Further innovation is needed to enhance treatment outcomes and expand clinical applications.
Continued research will drive advancements in endovascular stroke treatment.