Sleep disturbance in pediatric patients on automated peritoneal dialysis

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Cláudia Gomes1, Lia Oliveira1, Rosário Ferreira2

  • 1Department of Pediatrics, Hospital de Santa Maria, CHLN - Academic Medical Centre of Lisbon, Lisbon, Portugal.

Sleep Medicine
|April 4, 2017
PubMed

Insights

Sleep disturbance is common in children on automated peritoneal dialysis (APD), affecting over half of patients. Polysomnography (PSG) revealed decreased sleep efficiency and increased awake time, highlighting the need for screening in pediatric chronic kidney disease (CKD).

Area of Science:

  • Pediatric Nephrology
  • Sleep Medicine
  • Clinical Research

Background:

  • Limited research exists on sleep disturbance (SD) in children undergoing automated peritoneal dialysis (APD).
  • Previous studies primarily relied on questionnaires, with few utilizing polysomnography (PSG), the diagnostic gold standard.
  • This study represents the first assessment of SD in children with chronic kidney disease (CKD) on APD within the country.

Purpose of the Study:

  • To investigate the prevalence and characteristics of sleep disturbance in children with CKD treated with APD.
  • To compare objective PSG findings with subjective reports from a sleep questionnaire.

Main Methods:

  • An observational, descriptive study involving children under 18 on APD for at least three months.
  • Exclusion criteria included diabetes, neurological disorders, and sedative/hypnotic use.
  • Polysomnography (PSG) was conducted during nocturnal dialysis, followed by a sleep questionnaire on the same day.

Main Results:

  • Eight children (median age 10 years) on APD were studied.
  • Sleep disturbance was identified in 62.5% of patients via PSG.
  • PSG revealed reduced sleep efficiency, prolonged sleep latency, increased awake time, and elevated apnea/hypopnea and desaturation indices.

Conclusions:

  • Over half of the studied children on APD experienced sleep disturbance.
  • Subjective questionnaire data underestimated the objective findings from PSG.
  • Systematic screening for sleep problems is recommended for children with CKD on APD, with a low threshold for formal PSG.
Abstract

Keywords:
ChildrenPeritoneal dialysisPolysomnographySleep disturbance

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