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Published on: October 12, 2017
Lipid abnormalities in patients with Rheumatoid Arthritis
Uzma Erum1, Tasnim Ahsan2, Danish Khowaja3
1Dr. Uzma Erum, MBBS, FCPS Trainee. Medical Unit-II, Rafiqee Shaheed Road, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
Dyslipidemia, characterized by abnormal lipid levels, is common in Rheumatoid Arthritis (RA) patients. Early detection and management of these lipid abnormalities are crucial for reducing cardiovascular disease risk.
Area of Science:
- Rheumatology
- Cardiovascular Health
- Metabolic Disorders
Background:
- Rheumatoid Arthritis (RA) is a chronic inflammatory disease.
- RA is associated with an increased risk of cardiovascular disease.
- Dyslipidemia is a known risk factor for cardiovascular disease.
Purpose of the Study:
- To investigate the prevalence of dyslipidemia in patients diagnosed with Rheumatoid Arthritis.
- To identify specific lipid abnormalities common in RA patients.
Main Methods:
- A prospective, cross-sectional, observational study was conducted.
- 200 patients with Rheumatoid Arthritis were enrolled.
- Fasting lipid profiles were analyzed to assess dyslipidemia.
Main Results:
- Over half of the patients (53.5%) exhibited dyslipidemia.
- Low HDL cholesterol was the most frequent abnormality (41.5%).
- The study included a majority of female patients (88.5%).
Conclusions:
- Dyslipidemia is frequently observed in Rheumatoid Arthritis patients.
- This may be linked to the chronic inflammatory state characteristic of RA.
- Regular screening for lipid abnormalities and timely intervention are recommended to mitigate cardiovascular risk.
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