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An S antigen gene from Plasmodium falciparum contains a novel repetitive sequence
S C Nicholls1, Y Hillman, M J Lockyer
1Department of Molecular Biology, Wellcome Biotech, Beckenham, U.K.
Molecular and Biochemical Parasitology
|February 1, 1988
Abstract:
The complete sequence of the gene coding for the S antigen from the Wellcome (West African) strain of Plasmodium falciparum has been obtained. It contains a central repetitive region consisting of 65 copies of a partially degenerate 24 bp sequence, coding for a conserved 8 amino acid repeat (Gly Pro Asn Ser Asp Gly Asp Lys). The repeat sequence is different from those of S antigens characterised in other strains and thus represents a new S antigen serotype.