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Pharmacokinetics of a spin-labeled rubomycin analog
N P Konovalova1, R F Diatchkovskaya, G V Kukushkina
1Institute of Chemical Physics, Academy of Sciences of the USSR, Moscow.
Neoplasma
|January 1, 1988
Abstract:
Pharmacokinetics of a spin-labeled analog of rubomycin (ruboxyl) was studied. Differences were found in ruboxyl pharmacokinetics in normal and tumor-bearing animals. Most of the drug was excreted within 6 h. The differences in pharmacokinetics of ruboxyl and nitroxyl radical were established.