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Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis
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Published on: January 8, 2017

A self-assembled amphiphilic imidazolium-based ATP probe

Jiang-Hua Zhu1, Chuan Yu2, Yong Chen2

  • 1Department of Chemistry, Nanchang University, Nanchang 330031, P. R. China. cqyong@ncu.edu.cn.

Chemical Communications (Cambridge, England)
|April 4, 2017
PubMed

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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...