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Vitamin D Levels Do Not Predict Risk of Metatarsal Fractures.

Benjamin R Williams1,2,3, Avis J Thomas1,2,3, Rachel C Collier1,2,3

  • 1Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota (BRW, SAA).

Foot & Ankle Specialist
|April 4, 2017
PubMed
Summary
This summary is machine-generated.

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Vitamin D insufficiency is common in patients with low-energy foot and ankle injuries. This study found no significant difference in vitamin D levels between metatarsal fractures and sprains.

Area of Science:

  • Orthopedic Surgery
  • Endocrinology
  • Nutritional Science

Background:

  • Conflicting literature exists on vitamin D and fracture risk.
  • Limited data addresses vitamin D levels in foot and ankle pathologies.
  • Hypovitaminosis D is a potential concern in orthopedic trauma.

Purpose of the Study:

  • To determine the prevalence of vitamin D insufficiency in patients with low-energy metatarsal fractures.
  • To compare vitamin D levels in metatarsal fracture patients versus those with foot or ankle sprains.
  • To investigate the association between vitamin D status and low-energy foot and ankle injuries.

Main Methods:

  • Prospective case-control study (Level III) involving 99 patients.
  • Collected prospective data on vitamin D levels and demographics from May 2012 to August 2014.
Keywords:
25-hydroxyvitamin Dhypovitaminosismetatarsal fracturesvitamin D

Related Experiment Videos

  • Compared 71 patients with metatarsal fractures to 28 patients with sprains, all from low-energy mechanisms.
  • Main Results:

    • Mean vitamin D levels were similar between groups: 26.9 ng/mL (fractures) and 27.1 ng/mL (sprains).
    • Vitamin D insufficiency (<30 ng/mL) was highly prevalent in both groups: 66% of fracture patients and 71% of sprain patients.
    • No statistically significant difference (P = .81) in vitamin D insufficiency incidence was observed between the groups.

    Conclusions:

    • A high incidence of hypovitaminosis D (vitamin D deficiency) is present in patients with foot and ankle injuries.
    • Vitamin D levels do not differ significantly between patients experiencing low-energy metatarsal fractures and those with similar sprains.
    • Further research may be warranted to explore the role of vitamin D in bone health and injury prevention in the foot and ankle.