Related Experiment Videos
Clinical Profile, Management, and Outcome in Patients With Out-of-Hospital Cardiac Arrest and ST Segment Elevation
Abdul Rahman Arabi1, Ashfaq Patel1, Jassim Al Suwaidi1
11 Cardiology Department, Heart Hospital, Hamad Medical Corporation (HMC), Doha, Qatar.
Insights
Patients with out-of-hospital cardiac arrest (OHCA) and ST-elevation myocardial infarction (STEMI) were younger and more likely male. Management improved, with increased thrombolytic therapy and percutaneous coronary intervention, leading to reduced in-hospital mortality.
Area of Science:
- Cardiology
- Emergency Medicine
- Public Health
Background:
- Out-of-hospital cardiac arrest (OHCA) is a critical medical emergency with varying outcomes.
- ST-elevation myocardial infarction (STEMI) is a specific type of heart attack requiring prompt intervention.
- Understanding the differences in clinical profiles and outcomes between OHCA with and without STEMI is crucial for effective management.
Purpose of the Study:
- To compare the clinical characteristics, management strategies, and outcomes of patients experiencing OHCA with STEMI versus those without STEMI.
- To analyze trends in treatment and mortality over a 20-year period.
Main Methods:
- Retrospective analysis of a 20-year registry (1991-2010) of OHCA patients admitted to Hamad General Hospital and Qatar Heart Hospital.
- Comparison of demographic, clinical, and treatment data between OHCA patients with and without STEMI.
Main Results:
- A total of 987 OHCA patients were analyzed; 30% had STEMI.
- OHCA patients with STEMI were younger, more frequently male, and smokers, but had lower rates of hypertension, diabetes, and chronic renal failure compared to those without STEMI.
- Thrombolytic treatment for STEMI increased significantly over the study period (21.6% to 44.4%).
Conclusions:
- Percutaneous coronary intervention (PCI) use increased significantly in the latter part of the study.
- In-hospital mortality for STEMI patients showed a decline in the last quarter of the study period.
- These findings highlight evolving management strategies and improving outcomes for OHCA patients with STEMI.
Aim Of The Study:
We studied the clinical profile, management, and outcomes of patients with out-of-hospital cardiac arrest (OHCA) with and without ST-elevation myocardial infarction (STEMI).
Methods:
Retrospective analysis of the 20-year registry data (January 1991- June 2010) was conducted on patients with cardiac disease hospitalized at Hamad General Hospital and Qatar Heart Hospital, Doha, Qatar.
Results:
A total of 987 patients with OHCA were admitted to the cardiology department during the study period; among them, 296 (30%) patients had STEMI. Compared to the patients with OHCA without STEMI, the patients who had OHCA with STEMI were younger (53 ± 13 vs 58 ± 16 years; P = .001), more likely to be male (78% vs 34%; P = .001), smokers (35% vs 14%) but less likely to have hypertension (30% vs 48%; P = .001), diabetes (32% vs 47%, P = .001), and chronic renal failure (3.4% vs 9%; P = .002). The use of thrombolytic treatment in patients with STEMI increased from 21.6% (period 1991-1095) to 44.4% (period 2006-2010); P = .04.
Conclusion:
Percutaneous coronary intervention had increased significantly during the last quarter of the study. There was a decline in the in-hospital mortality among patients with STEMI during the last quarter of the study.