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Related Experiment Videos

Ventricular dysfunction in children with obstructive sleep apnea: radionuclide assessment.

A Tal1, A Leiberman, G Margulis

  • 1Pediatric Division, Soroka University Hospital, Beer-Sheva, Israel.

Pediatric Pulmonology
|January 1, 1988
PubMed
Summary

Obstructive sleep apnea in children can impair right ventricular function, even before clinical signs of heart problems appear. Treatment, like adenotonsillectomy, significantly improves cardiac function.

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Area of Science:

  • Pediatric Cardiology
  • Sleep Medicine
  • Cardiopulmonary Physiology

Background:

  • Obstructive sleep apnea (OSA) in children is often linked to adenotonsillar hypertrophy.
  • Cardiac involvement in pediatric OSA is not always clinically apparent.
  • Ventricular dysfunction can be an early indicator of OSA-related complications.

Purpose of the Study:

  • To evaluate ventricular function in children with oropharyngeal obstruction and OSA.
  • To determine if OSA impacts right and left ventricular function.
  • To assess the effect of adenotonsillectomy on ventricular function in these children.

Main Methods:

  • Radionuclide ventriculography was used to assess ventricular function in 27 children with OSA.
  • Ejection fraction and wall motion abnormalities were analyzed.

Related Experiment Videos

  • Ventricular function was reassessed after adenotonsillectomy in a subset of patients.

    • Main Results:

    • Reduced right ventricular ejection fraction (<35%) was found in 37% of patients.
    • Wall motion abnormalities were detected in 18 patients.
    • Adenotonsillectomy significantly improved right ventricular ejection fraction (24.4% to 46.7%) and wall motion.

    Conclusions:

    • Right ventricular function can be compromised in children with OSA due to adenotonsillar hypertrophy.
    • Ventricular dysfunction may precede overt clinical signs of cardiac involvement.
    • Surgical removal of obstruction (adenotonsillectomy) can reverse cardiac dysfunction in pediatric OSA.