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Related Experiment Videos

Acute Heart Failure Triggered by Coronary Spasm With Transient Left Ventricular Dysfunction.

Yusuke Adachi1, Kenichi Sakakura, Tatsuro Ibe

  • 1Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.

International Heart Journal
|April 4, 2017
PubMed
Summary

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Coronary spasm, an abnormal artery contraction, can cause acute heart failure. The acetylcholine provocation test aids in diagnosing this condition and elevated ventricular filling pressure.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Coronary spasm involves abnormal contraction of epicardial coronary arteries, leading to myocardial ischemia.
  • This condition impairs myocardial contractility and relaxation, resulting in elevated ventricular filling pressure.

Observation:

  • A 55-year-old woman experienced recurrent acute heart failure attributed to coronary spasm.
  • The patient presented with symptoms suggestive of heart failure, prompting further investigation.

Findings:

  • Acetylcholine provocation testing combined with right heart catheterization effectively diagnosed both coronary artery spasm and elevated ventricular filling pressure.
  • Diagnostic confirmation was achieved through invasive hemodynamic monitoring and provocative testing.

Implications:

Related Experiment Videos

  • Coronary spasm should be considered in the differential diagnosis for patients with repeated episodes of acute heart failure.
  • Early recognition and diagnosis of coronary spasm can improve patient outcomes and guide appropriate management strategies.