Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quantitative Susceptibility Mapping Using the Multiple Dipole-inversion Combination with k-space Segmentation Method.

Ryota Sato1, Toru Shirai1, Yo Taniguchi1

  • 1Research and Development Group, Hitachi Ltd.

Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine
|April 4, 2017
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

WT1-Targeted Oral Bifidobacterium longum Vaccine Enhances Checkpoint Blockade Efficacy in Pancreatic Cancer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases.

Nature immunology·2026
Same author

Electroencephalogram-based Objective Assessment of Surgical Expertise during Microvascular Anastomosis Training.

Neurologia medico-chirurgica·2026
Same author

Response to "Repositioning POCUS in the Diagnostic Landscape of Gastric Anisakiasis: A Call Toward Pragmatic Integration".

Acute medicine & surgery·2026
Same author

Efgartigimod as a Steroid-sparing Therapy for Evans Syndrome: A Case Report.

Internal medicine (Tokyo, Japan)·2026
Same author

Advancement of humanized mice and leading applications in immunological disease models.

Inflammation and regeneration·2026

Quantitative susceptibility mapping (QSM) using the novel MUDICK method improves small vein visualization in MRI. This technique enhances accuracy and contrast of small veins without causing streaking artifacts.

Area of Science:

  • Medical Imaging
  • Biophysics
  • Neuroimaging

Background:

  • Quantitative susceptibility mapping (QSM) estimates tissue magnetic susceptibility using MRI.
  • Conventional QSM methods accurately image deep gray matter but struggle with small veins due to inconsistent contrast.
  • Underestimation and poor depiction of small veins limit the diagnostic potential of existing QSM techniques.

Purpose of the Study:

  • To introduce and evaluate a novel QSM method, MUDICK (multiple dipole-inversion combination with k-space segmentation).
  • To improve the accuracy and visibility of small veins in susceptibility maps.
  • To reduce streaking artifacts often associated with QSM.

Main Methods:

  • The MUDICK method segments k-space data into low-frequency, magic-angle, and high-frequency domains.
Keywords:
k-spacequantitative susceptibility mappingregularizationvein

Related Experiment Videos

  • L1-norm regularization with structural information was used for low-frequency and magic-angle domains.
  • High-frequency domain data were utilized from a pre-estimated susceptibility map to preserve small vein details.

    • Main Results:

    • Numerical simulations and human brain studies at 3 Tesla were conducted.
    • MUDICK and MEDI methods demonstrated no severe streaking artifacts.
    • MUDICK exhibited superior contrast and accuracy in depicting small vein susceptibility compared to MEDI.

    Conclusions:

    • The MUDICK method effectively enhances the accuracy and visibility of small veins in QSM.
    • MUDICK overcomes limitations of conventional methods by preserving small vein contrast.
    • This technique offers improved noninvasive assessment of microvasculature in the brain.