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Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis
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[Extensive osteolytic calotte destructions in primary breast cancer]

K Hornig1

  • 1Strahlenklinik, Allgemeinen Krankenhauses für die Stadt Hagen.

Der Radiologe
|March 1, 1988
PubMed

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...