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Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
09:11

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Published on: August 23, 2016

Zika virus: A public health threat

Shashi Sharma1, Kundan Tandel1, Paban K Dash1

  • 1Virology Division, Defence Research and Development Establishment (DRDE), Gwalior, Madhya Pradesh, India.

Journal of Medical Virology
|April 4, 2017
PubMed

Insights

Zika virus resurgence, linked to microcephaly, demands scientific understanding. This review details Zika virus evolution from its origins to inform public health strategies.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • Zika virus (ZIKV) re-emerged as a significant global health threat.
  • Increased incidence of microcephaly cases correlated with ZIKV outbreaks.
  • Urgent need for comprehensive understanding of ZIKV's biological and epidemiological characteristics.

Purpose of the Study:

  • To provide an updated review on Zika virus evolution.
  • To consolidate current knowledge on ZIKV's historical development and trajectory.

Main Methods:

  • Literature review of scientific publications on Zika virus.
  • Analysis of data on ZIKV's genetic, epidemiological, and geographical changes.
  • Synthesis of information regarding ZIKV's evolutionary timeline.

Main Results:

  • Detailed account of Zika virus evolution since its emergence.
  • Insights into the factors driving ZIKV's geographical spread and adaptation.
  • Understanding of ZIKV's pathogenic evolution in relation to human health.

Conclusions:

  • Continued monitoring of Zika virus evolution is crucial.
  • Understanding evolutionary dynamics aids in predicting and managing future outbreaks.
  • This review provides a foundation for further research into ZIKV pathogenesis and control.
Keywords:
emergencemicrocephalyphylogenyvectorzika virus

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